Accession Number : ADP013607


Title :   Oligonucleofide Imprinting in Aqueous Environment


Descriptive Note : Conference paper


Corporate Author : CALIFORNIA UNIV IRVINE DEPT OF CHEMISTRY


Personal Author(s) : Batra, Dolly ; Shea, Kenneth J.


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADP013607


Report Date : 05 APR 2002


Pagination or Media Count : 8


Abstract : The development of synthetic receptors that recognize nucleotide bases and their derivatives is an important area of research 1-3. Applications are envisioned in separation science, biosensors, drug therapy and genetic engineering. Previously in this laboratory, we have developed a molecularly imprinted synthetic receptor for 9-ethyladenine (9-EA). The network polymer has an affinity for adenine and its derivatives with an average association constant (K(a)) of 75,000 M(-1) in CHCl3.


Descriptors :   *POLYMERS , POLYMERIZATION , MACROMOLECULES , MONOMERS , SOLVATION , ORGANIC SOLVENTS , OLIGOMERS , FORMULATIONS(CHEMISTRY) , PHOSPHITES , NUCLEOTIDES , ADENINE , GUANINE , AQUEOUS SOLUTIONS.


Subject Categories : POLYMER CHEMISTRY


Distribution Statement : APPROVED FOR PUBLIC RELEASE