Accession Number : ADA578704


Title :   Critical Review of Selected Components of RIPD (Radiation-Induced Performance Decrement)


Descriptive Note : Technical rept. Dec 2010-Dec 2012


Corporate Author : APPLIED RESEARCH ASSOCIATES INC ARLINGTON VA


Personal Author(s) : Pellmar, Terry C ; Oldson, Darren R


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA578704


Report Date : Dec 2012


Pagination or Media Count : 43


Abstract : RIPD (Radiation-Induced Performance Decrement) is a physiologically-based model of acute radiation sickness (ARS). RIPD estimates: severity of illness due to prompt or protracted exposures to ionizing radiation for total free-in-air doses between 0.75 Gy and 45 Gy; residual performance capability over time for soldiers exposed to ionizing radiation in a military engagement; incidence of performance decrement; incidence of lethality; time to lethality. The RIPD model applies to whole-body exposures to gamma rays and/or neutrons; dose-rate histories can be complex and the exposure period can be as long as one week. RIPD estimates severity of illness and performance capability for up to 1000 hours (about 6 weeks) after the start of exposure. The prompt exposure models in RIPD were developed during the Defense Nuclear Agency's Intermediate Dose Program (IDP) to facilitate consequence assessment and military planning in a nuclear radiation environment. This report (1) summarizes RIPD's performance decrement model, and (2) reviews the four kinetic models around which RIPD's sign/symptom (S/S) severity model structure is built and through which RIPD extends the IDP's prompt exposure S/S severity models to protracted radiation exposures. The assumptions, limitations, and mathematical structure of these four physiologically-based models are discussed.


Descriptors :   *RADIATION SICKNESS, LETHALITY, MODELS, NUCLEAR RADIATION, PERFORMANCE(HUMAN), RADIATION INJURIES


Subject Categories : Radiobiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE