Accession Number : ADA545786


Title :   Optimization of Breast Tomosynthesis Imaging Systems for Computer-Aided Detection


Descriptive Note : Annual summary rept. 1 May 2008-30 Apr 2011


Corporate Author : CHICAGO UNIV IL


Personal Author(s) : Lau, Beverly


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA545786


Report Date : MAY 2011


Pagination or Media Count : 30


Abstract : The goal of this research is to develop methodology for optimizing acquisition parameters for digital tomosynthesis of the breast (DBT). Optimization is important to be able to study whether DBT can be used in place of screening mammography with better sensitivity and specificity. The research is composed of three parts: 1) to develop a computer model to simulate tomosynthesis, 2) to generate realistic breast and tumor models, and 3) to determine optimal acquisition parameters by using a genetic algorithm with CADe performance as an indicator of fitness. In this report, we summarize the research done for this project to date, focussing particularly on the development of an anthropomorphic software breast phantom and its validation. Lastly, we evaluate methods for measuring anatomic noise in projection imaging.


Descriptors :   *COMPUTER AIDED DIAGNOSIS , *MAMMOGRAPHY , *TOMOGRAPHY , NEOPLASMS , NOISE , ANATOMY , DETECTION , DIGITAL SYSTEMS , COMPUTERIZED SIMULATION , COMPUTER APPLICATIONS


Subject Categories : MEDICINE AND MEDICAL RESEARCH
      MEDICAL FACILITIES, EQUIPMENT AND SUPPLIES


Distribution Statement : APPROVED FOR PUBLIC RELEASE