Accession Number : ADA508506


Title :   Cone-Beam Computed Tomography for Image-Guided Radiation Therapy of Prostate Cancer


Descriptive Note : Annual summary 11 Dec 2007-11 Dec 2008


Corporate Author : CHICAGO UNIV IL


Personal Author(s) : Cho, Seungryong


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA508506


Report Date : JAN 2009


Pagination or Media Count : 53


Abstract : The success of intensity-modulated radiation therapy (IMRT) or 4-D conformal radiation therapy (CRT) is heavily reliant on accurate image-guidance in prostate cancer treatment. Cone-beam computed tomography (CBCT) is becoming one of the dominant imaging modalities for image-guidance, but current technology based on Feldkamp algorithm for image reconstruction from a circular scanning trajectory does not yield sufficient quality of images. In addition, imaging-radiation dose is one of the key issues, which has to be minimized or optimized. We report our continued research on CBCT scanning methods and corresponding image reconstruction algorithms that can increase the accuracy of the images and/or reduce patient dose from CBCT. A BPF-FBP tandem algorithm for reverse helical CBCT has been developed, intensity-weighted region-of-interest image reconstruction methods have been explored, and a prior-image-based few-view CBCT approach has been proposed.


Descriptors :   *PROSTATE CANCER , *RADIATION , *COMPUTERIZED TOMOGRAPHY , ACCURACY , DOSAGE , THERAPY , PATIENTS , MODULATION , TRAJECTORIES , CIRCULAR , CATHODE RAY TUBES , CHEMOTHERAPY , SCANNERS , RADIOTHERAPY , INTENSITY , IMAGE RECONSTRUCTION , SCANNING , ALGORITHMS


Subject Categories : ANATOMY AND PHYSIOLOGY
      MEDICINE AND MEDICAL RESEARCH
      RADIOBIOLOGY
      COMPUTER PROGRAMMING AND SOFTWARE


Distribution Statement : APPROVED FOR PUBLIC RELEASE