Accession Number : ADA480740


Title :   A Software Pipeline for Protein Structure Prediction


Descriptive Note : Conference paper


Corporate Author : ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD


Personal Author(s) : Lee, Michael S. ; Yeh, In-Chul ; Zavajevski, Nela ; Wilson, Paul ; Reifman, Jaques


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA480740


Report Date : NOV 2006


Pagination or Media Count : 9


Abstract : We have developed a software suite to predict protein structures from sequence through the integration of multiple non-commercial programs. The Army and DoD medical and scientific communities will be able to use this software to annotate structures of sequenced pathogenic and host genomes. Such structural predictions can be used in therapeutic and vaccine design as well as many areas of basic biological research. In this work, initial assessments of the software are made. Most importantly, these tests include evaluation of the quality of predicted structural models as a function of sequence similarity to known protein structures.


Descriptors :   *SOFTWARE ENGINEERING , *PROTEINS , TEST AND EVALUATION , TEST METHODS , PATHOGENESIS , SOFTWARE TOOLS , GENOME , VACCINES , SEQUENCES , SYMPOSIA , MODELS


Subject Categories : COMPUTER PROGRAMMING AND SOFTWARE
      BIOCHEMISRTY
      BIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE