Accession Number : ADA427170
Title : Anti-Angiogenic Gene Therapy for Prostate Cancer
Descriptive Note : Annual rept.
Corporate Author : ALABAMA UNIV IN BIRMINGHAM
Personal Author(s) : Ponnazhagan, Selvarangan
Report Date : Apr 2004
Pagination or Media Count : 61
Abstract : One of the major implications of prostate cancer progression is bone metastasis. Primary therapies for neoplastic prostate disease have been prostectomy followed by chemotherapy and radiation therapy. Although these forms of palliative therapies have been successful in early detected prostate cancers, a problem in majority of the treated cases is the growth of radiation/chemotherapy resistant tumor cells, which become refractory to treatment and exhibit an aggressive growth and metastatic profile. Thus, novel therapies that will control the process of recurrence and metastasis will have a profound clinical implication in the management of prostate cancer patients who undergo primary therapies.
Descriptors : *PROSTATE CANCER , *ANGIOGENESIS , DISEASES , NEOPLASMS , PROFILES , THERAPY , PATIENTS , BLOOD VESSELS , GENE THERAPY , CHEMOTHERAPY , BONES , GROWTH(PHYSIOLOGY) , PROSTATE GLAND , METASTASIS , RADIOTHERAPY
Subject Categories : Genetic Engineering and Molecular Biology
Anatomy and Physiology
Medicine and Medical Research
Distribution Statement : APPROVED FOR PUBLIC RELEASE