Accession Number : ADA207307


Title :   Symposium on Animal Retroviruses: Abstracts. Held in Denver, Colorado on 10 December 1986


Corporate Author : ILLINOIS UNIV AT URBANA-CHAMPAIGN


Personal Author(s) : Ristic, Miodrag


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA207307


Report Date : 10 DEC 1986


Pagination or Media Count : 16


Abstract : Studies on murine, feline, and ungulate retroviruses have provided background and direction for much of the research on human retroviruses and the pathogenesis of leukemia and immunosuppression. The relevance of animal model systems for retroviral induced disease is particularly important because of recently discovered human retroviruses. There are presently four known members of the human T-lymphotropic virus (HTLV) family; at least two of these have been strongly implicated as the etiologic agent of clinically significant human disease. HTLV type I (HTVL-I) has been etiologically linked with the development of a unique human leukemia, termed Adult T-Cell Leukemia/Lymphoma. HTLV type II (HTLV-II) was originally isolated from a T-cell variant of hairy cell leukemia. It is closely related to HTLV-I; however, its role in human disease is still not clear. HTLV type III (HTLV-III), also known as LAV,ARV-2, and HIV, is the cause of AIDS. A Fourth T-lymphotropic virus has recently been isolated from a number of healthy individuals from West Africa and designated HTLV-IV. Keywords: RA 1; Symposium; Retroviruses; ASTVM; BD.


Descriptors :   *ANIMALS , *VIRUSES , HUMANS , DISEASES , ETIOLOGY , WEST AFRICA , SYMPOSIA , PATHOGENESIS , IMMUNOSUPPRESSION , MODELS , LEUKEMIA


Subject Categories : BIOLOGY
      MICROBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE