Accession Number : ADA104813


Title :   Diagnosis of Group A Streptococcal Infections Directly From Throat Gargle.


Descriptive Note : Final rept.,


Corporate Author : NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA


Personal Author(s) : Edwards,E A ; Phillips,I A ; Suiter,W C


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA104813


Report Date : Jun 1981


Pagination or Media Count : 9


Abstract : The diagnosis of group A streptococcal disease still relies on isolation on sheep blood agar followed by presumptive identification of group A streptococcal strains by using bacitracin sensitivity or the more precise sero-grouping methods such as the Lancefield precipitin test. A technique that would permit rapid identification of streptococcal infections directly from throat secretions would allow immediate appropriate antimicrobial therapy in the management of streptococcal infections. We have been able to identify soluble Group A antigen directly from throat gargle by using a latex aggregation test. In a clinical trial using latex (Streptex group A) 53 throat culture/gargles were taken, 31 were culture positive, and 29 were latex positive for group A streptococcal antigen. (Author)


Descriptors :   *DIAGNOSIS(MEDICINE) , *INFECTIOUS DISEASES , *STREPTOCOCCUS , *THROAT , DETECTION , ISOLATION , TEST METHODS , IDENTIFICATION , ANTIGENS , CULTURES(BIOLOGY) , SECRETION


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE