Accession Number : ADA033823


Title :   Pneumococcal Meningitis in a Rhesus Monkey.


Descriptive Note : Interim rept.,


Corporate Author : ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD


Personal Author(s) : Faulkner,Roy T ; Burger,Gary T ; Harrington,Donald G ; Hickman,Robert L


Full Text : http://www.dtic.mil/dtic/tr/fulltext/u2/a033823.pdf


Report Date : 17 Dec 1976


Pagination or Media Count : 24


Abstract : A recently acquired young, 2.8-kg male rhesus monkey (Macaca mulatta) demonstrated a peculiar behavioral pattern, depression, and anorexia. Approximately 40 hr later, hyperestheisa, generalized muscle tremors, ataxia, and nystagmus became apparent. Cerebrospinal fluid contained numerous gram-positive cocci; subsequently, pure cultures of Streptococcus (Diplococcus) pneumoniae were isolated. Extensive antibiotic and supportive treatment for pneumococcal meningitis was administrated for 12 da. The monkey appeared to respond to treatment, but 9 da following cessation of all treatment, the monkey demonstrated residual central nervous system signs which progressed until the animal was euthanatized 3 wk later. (Author)


Descriptors :   *MENINGITIS , *STREPTOCOCCAL PNEUMONIA , SIGNS AND SYMPTOMS , THERAPY , PATHOLOGY , RHESUS MONKEYS , BLOOD ANALYSIS , CEREBROSPINAL FLUID


Subject Categories : Animal Husbandry and Veterinary Medicine
      Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE