Accession Number : ADA033589


Title :   Classical Conditioning of Hippocampal Theta Patterns in the Rat.


Descriptive Note : Scientific rept.,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Teitelbaum ,H. ; McFarland,W. L. ; Mattsson,J. L.


Report Date : AUG 1976


Pagination or Media Count : 14


Abstract : Electrical stimulation (88 Hz) of the lateral hypothalamus elicits a sustained theta response at hippocampal recording sites of rats immobilized with succinylcholine. By pairing this unconditioned stimulus with a 10-second presentation of a light, conditioned theta responses consistently appear after 40 trials. When the conditioned rats were tested in the absence of a neuromuscular blocking agent, the conditioned stimulus elicited a theta response that was associated with slow locomotor activity in 70 percent of the trials. This paper provides an assay for hippocampal bioelectric activity that is useful in understanding radiation-induced behavioral incapacitation. (Author)


Descriptors :   *CONDITIONING(LEARNING), *HYPOTHALAMUS, STIMULATION(PHYSIOLOGY), RATS, BEHAVIOR, BIOELECTRICITY, NEUROCHEMICAL TRANSMISSION.


Subject Categories : PSYCHOLOGY
      ANATOMY AND PHYSIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE