Accession Number : ADA033411


Title :   A Method of Measuring Thyroid Burden of I125.


Descriptive Note : Technical note,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Webber,W. R. ; Donovan,R. L.


Report Date : JUN 1976


Pagination or Media Count : 12


Abstract : Laboratory workers producing I125 labeled compounds may ingest or inhale small quantities of radioactive iodine which is deposited preferentially in the thyroid. Measurement of the thyroid burden is required to quantify the radiation dose to the individual and to provide early warning of possible health hazards. A rapid, accurate method of measuring thyroid burden using an Anger camera and pulse height analysis techniques was developed. The procedure requires 2 to 3 minutes, equipment commonly available in a nuclear medicine department, and causes no discomfort for the subject. The minimum detectable amount of I125 has been found to be approx. 1.0 nCi with a counting time of 100 seconds. The linearity of the method has been measured using on ORINS thyroid phantom and sources traceable to the NBS. The method is in regular use at the AFRRI and some results obtained from this use are presented. (Author)


Descriptors :   *THYROID GLAND, *IODINE, *RADIOACTIVE ISOTOPES, DETECTION, HAZARDS, COUNTING METHODS, CAMERAS, DOSAGE, CADMIUM, HEALTH SURVEYS, RADIATION MEASURING INSTRUMENTS, INHALATION, PULSE HEIGHT ANALYZERS, INGESTION(PHYSIOLOGY), NUCLEAR MEDICINE.


Subject Categories : RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE