Accession Number : ADA033407


Title :   Cardiac Arrhythmias Resulting from Experimental Head Injury.


Descriptive Note : Scientific rept.,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Evans,D E ; Alter,W A , III ; Shatsky,S A ; Parkhurst,L J ; Gunby,E N


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=ADA033407


Report Date : Jul 1976


Pagination or Media Count : 16


Abstract : The cardiovascular events resulting from experimental head injury were studied to determine the incidence of cardiac arrhythmias and to define the autonomic mechanisms responsible for these changes. The electrocardiogram and arterial blood pressure were recorded in anesthetized monkeys before and after the animals were subjected to temporoparietal head impact. Cardiac arrhythmias and hypotension occurred immediately following impact in every animal studied. Various A-V nodal and ventricular arrhythmias were seen. Cholinergic blockade was found to prevent arrhythmias induced by head injury whereas adrenergic blockade was found to be ineffective. These results suggest that in human head injury, the cardiovascular events alone may be life-threatening. Since head trauma is a common cause of injury and death of military personnel in both combat and peacetime situations, early evaluation of the cardiovascular status of the head injured patient should be stressed. (Author)


Descriptors :   *WOUNDS AND INJURIES, *HEAD(ANATOMY), *ARRHYTHMIA, MILITARY PERSONNEL, LABORATORY TESTS, CLINICAL MEDICINE, CARDIOVASCULAR SYSTEM, ARTERIES, AUTONOMIC NERVOUS SYSTEM, BLOOD PRESSURE, ELECTROCARDIOGRAPHY, MONKEYS, TRAUMATIC SHOCK, VENTRICLES, ANESTHETICS, PARASYMPATHOLYTIC AGENTS, HYPOTENSION


Subject Categories : Medicine and Medical Research


Distribution Statement : APPROVED FOR PUBLIC RELEASE