Accession Number : ADA033257


Title :   The Electrical Resistivity of Aqueous Cytoplasm,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Foster,K. R. ; Bidinger,J. M. ; Carpenter,D. O.


Report Date : AUG 1976


Pagination or Media Count : 25


Abstract : The mechanism of radiation damage of all cells is critical to an understanding of radiation damage in man and the development of methods of treatment and protection; and studies of cell membranes and cytoplasm constitute a highly specific and valuable method of approaching the problem of how radiation affects cellular function. In these experiments, the apparent cytoplasmic resistivity of two different giant cells has been measured using an extension of a previously developed single microelectrode technique. Each cell is penetrated by a metal microelectrode whose complex impedance is measured as a function of frequency between 500 kHz and 5.7 MHz. By plotting the measured impedance data on the complex Z plane and extrapolating the data to infinite frequency, the substantial effects of electrode polarization can be overcome. For Aplysia giant neurons and muscle fibers of the giant barnacle, the extrapolated cytoplasmic specific resistivities are 40 and 74 ohm-cm, respectively, at infinite frequency.


Descriptors :   *ELECTRICAL CONDUCTIVITY, *CYTOPLASM, POLARIZATION, MEMBRANES(BIOLOGY), SOLUTIONS(MIXTURES), WATER, ELECTRODES, MICROELECTRONICS, MARINE BIOLOGY, NERVOUS SYSTEM, NERVE CELLS, CELLS(BIOLOGY), AQUATIC ORGANISMS, BARNACLES, IONIZING RADIATION, MUSCLE FIBERS, RADIATION INJURIES, ELECTROLYTES(PHYSIOLOGY).


Subject Categories : ANATOMY AND PHYSIOLOGY
      ELECTRICITY AND MAGNETISM


Distribution Statement : APPROVED FOR PUBLIC RELEASE