Accession Number : ADA020381
Title : Dopamine Uptake in the Somatic Cell Hybrid NX31.
Descriptive Note : Scientific rept.,
Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Personal Author(s) : Myers,P. R. ; Shain,W. G. , Jr
Report Date : AUG 1975
Pagination or Media Count : 32
Abstract : The authors have investigated the kinetics and pharmacology of membrane transport of 3,4-dihydroxyphenylethylamine (dopamine) in the neuroblastoma clone N18TG2 and mouse sympathetic ganglion cells. NX31 was grown in exponential growth phase and in the presence of dibutyryl cyclic adenosine monophosphate, a compound known to initiate morphological and biochemical modulation, in order to investigate possible transitions in kinetic properties during differentiation.
Descriptors : *NEUROCHEMISTRY, *CATECHOLAMINES, *DOPAMINE, TISSUE CULTURE CELLS, METABOLISM, IN VITRO ANALYSIS, TRANSPORT PROPERTIES, PHARMACOLOGY, BIOLOGICAL ABSORPTION, NUCLEOTIDES, NEUROCHEMICAL TRANSMISSION.
Subject Categories : BIOCHEMISRTY
Distribution Statement : APPROVED FOR PUBLIC RELEASE