Accession Number : ADA020381
Title : Dopamine Uptake in the Somatic Cell Hybrid NX31
Descriptive Note : Scientific rept.
Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Personal Author(s) : Myers, P R ; Shain, Jr, W G
Report Date : Aug 1975
Pagination or Media Count : 32
Abstract : The authors have investigated the kinetics and pharmacology of membrane transport of 3,4-dihydroxyphenylethylamine (dopamine) in the neuroblastoma clone N18TG2 and mouse sympathetic ganglion cells. NX31 was grown in exponential growth phase and in the presence of dibutyryl cyclic adenosine monophosphate, a compound known to initiate morphological and biochemical modulation, in order to investigate possible transitions in kinetic properties during differentiation.
Descriptors : *CATECHOLAMINES , *DOPAMINE , *NEUROCHEMISTRY , BIOLOGICAL ABSORPTION , IN VITRO ANALYSIS , METABOLISM , NEUROCHEMICAL TRANSMISSION , NUCLEOTIDES , PHARMACOLOGY , TISSUE CULTURE CELLS , TRANSPORT PROPERTIES
Subject Categories : Biochemistry
Distribution Statement : APPROVED FOR PUBLIC RELEASE