Accession Number : ADA010819


Title :   The Effects of Traumatic Injury on Spinal Cord Blood Flow.


Descriptive Note : Scientific rept.,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Doyle,T. F. ; Kobrine,A. I. ; Martins,A. N.


Report Date : DEC 1974


Pagination or Media Count : 19


Abstract : Using the hydrogen clearance technique, the effect of direct crush injury on blood flow was measured in the lateral white matter and central gray matter of the spinal cord of the adult rhesus monkey. Three measurements were made: at the site of injury (T8-T10), 1 cm above and 1 cm below. After injury, blood flow in the central gray matter declined markedly. However, flow in the lateral funiculus increased 100 percent or more within 2 hours after injury, and then returned to normal range by 8 hours where it remained for at least 24 hours. These data contradict the prevailing theory of a progressive ischemia in the lateral white matter secondary to the development of a hemorrhagic infarct in the central gray matter as a mechanism in crush injury of the cord.


Descriptors :   *WOUNDS AND INJURIES, *BLOOD CIRCULATION, *SPINAL CORD, EXPERIMENTAL DATA, MONKEYS, PARALYSIS.


Subject Categories : MEDICINE AND MEDICAL RESEARCH


Distribution Statement : APPROVED FOR PUBLIC RELEASE