Accession Number : ADA001267


Title :   Augmentation of Regional Cerebral Blood Flow by Microvascular Anastomosis.


Descriptive Note : Scientific rept.,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Fein,J. M. ; Molinari,G. F. ; Parkhurst,L. J.


Report Date : JUN 1974


Pagination or Media Count : 19


Abstract : Intracranial surgical procedures for cerebrovascular occlusive disease have become feasible with the development of microvascular surgical techniques. This study assessed the ability of microanastomosis of the superficial temporal cortical artery to augment cerebral blood flow after clip occlusion of the middle cerebral artery in the dog. A variable degree of flow depression and consistent disruption of the blood-brain barrier occurred after occlusion. Augmentation of cerebral blood flow after anastomosis was associated with widening of the hysteresis loop obtained on autoregulatory testing but was unrelated to the degree of clinical recovery.


Descriptors :   *CEREBROVASCULAR SYSTEM, EXPERIMENTAL DATA, BRAIN, MODELS, THERAPY, SURGERY, DOGS, BLOOD CIRCULATION, ARTERIES, CEREBRUM, OBSTRUCTION(PHYSIOLOGY).


Subject Categories : MEDICINE AND MEDICAL RESEARCH


Distribution Statement : APPROVED FOR PUBLIC RELEASE