Accession Number : ADA000963


Title :   Mammalian Cold Receptor Afferents: Role of an Electrogenic Sodium Pump in Sensory Transduction.


Descriptive Note : Scientific rept.,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Carpenter,D. O. ; Pierau,Fr.-K. ; Torrey,P. J.


Report Date : JUL 1974


Pagination or Media Count : 13


Abstract : The responses of specific cold-sensitive afferents and cold-sensitive mechano-receptors were recorded from rat pudendal nerve. A local infiltration of ouabain into the region of the afferent terminals caused a dramatic increase in discharge at warm temperatures without significant effect on discharge in the cold. These results suggest that an electrogenic sodium pump is the generator potential mechanism imparting cold sensitivity. (Author)


Descriptors :   *SENSE ORGANS, LOW TEMPERATURE, EXPERIMENTAL DATA, MAMMALS, RATS, SODIUM, SENSITIVITY, SENSES(PHYSIOLOGY), NERVES, ELECTROLYTES(PHYSIOLOGY).


Subject Categories : ANATOMY AND PHYSIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE