Accession Number : AD1033001


Title :   Layer-by-Layer Bioprinting of Stem Cells for Retinal Tissue Regeneration


Descriptive Note : Technical Report,30 Sep 2014,29 Sep 2016


Corporate Author : University of California, San Diego La Jolla United States


Personal Author(s) : Chen,Shaochen ; Zhang,Kang


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD1033001


Report Date : 01 Dec 2016


Pagination or Media Count : 22


Abstract : We aim to investigate a Layer-by-Layer (LBL) bioprinting process using stem cells for retinal tissue regeneration. The LBL nature of the bioprinting process matches nicely with the native, multilaminar anatomy of the retina. This research will bioprint retinal stem cells (RSCs) and appropriate growth factors(GF) encapsulated in a biomaterial (e.g. hyaluronic acid, HA). We will investigate the mechanical, chemical and biological properties of the hydrogel materials. We will study the cell viability and analyze the biological functions of the 3D printed retina tissue.


Descriptors :   additive manufacturing , stem cells , REGENERATION (PHYSIOLOGY) , RETINA , growth factors , TISSUE ENGINEERING , biomaterials , HYDROGELS , mechanical properties , CHEMICAL PROPERTIES


Subject Categories : Anatomy and Physiology
      Medicine and Medical Research
      Printing and Graphic Arts


Distribution Statement : APPROVED FOR PUBLIC RELEASE