Accession Number : AD1013667


Title :   Sensitivity of Retinal Ganglion Cell Photoreceptors in Traumatic Brain Injury Patients with Photophobia


Descriptive Note : Technical Report,01 Sep 2012,31 Aug 2015


Corporate Author : Ohio State University Columbus United States


Personal Author(s) : Hartwick,Andrew T


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD1013667


Report Date : 01 Nov 2015


Pagination or Media Count : 28


Abstract : Intolerance to light, or photophobia, is a common symptom in individuals that have experienced traumatic braininjury (TBI). We investigated the light sensitivity of melanopsin-containing retinal ganglion cells in subjects that have had a prior head injury. These intrinsically photosensitive retinal ganglion cells (ipRGCs) act as irradiance detectors and signal information about ambient light levels. 28 subjects with prior TBI and photophobia were recruited for the study, with 24 completing two experimental sessions. 12 age-matched subjects participated in a control group.


Descriptors :   TRAUMATIC BRAIN INJURIES , wounds and injuries , Photosensitivity , eye , CIRCADIAN RHYTHMS


Distribution Statement : APPROVED FOR PUBLIC RELEASE