Accession Number : AD0764971


Title :   The Relative Effectiveness of Fission Neutrons for Gastrointestinal Damage in Mice: Jejunal Crypt Stem Cell Survival.


Descriptive Note : Scientific rept.,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Zeman,G. H. ; Jones,S. R. ; George,R. E. ; Levin,S. G.


Report Date : FEB 1973


Pagination or Media Count : 15


Abstract : Mice were unilaterally irradiated in either a fission neutron or gamma ray field at various dose rates. Jejunal crypt stem cell survival was analyzed by the multitarget single-hit survival model, which yielded excellent fitting survival curves. At the 1 percent survival level, gamma rays were found to be 20 percent more effective in destroying cells when delivered in a brief pulse of radiation than when delivered at lower dose rates (40 rads/minute or 250 rads/minute). Increased cell survival was not observed for low dose rate neutrons. Do values obtained were consistent with the findings of similar studies; however, survival curve intercepts were found to be lower than previous estimates. (Author)


Descriptors :   (*RADIATION INJURIES, *GASTROINTESTINAL SYSTEM), (*NEUTRON CAPTURE GAMMA RAYS, GASTROINTESTINAL SYSTEM), RADIATION DOSAGE, CELLS(BIOLOGY), SURVIVAL(PERSONNEL), DOSE RATE


Subject Categories : RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE