Accession Number : AD0764971
Title : The Relative Effectiveness of Fission Neutrons for Gastrointestinal Damage in Mice: Jejunal Crypt Stem Cell Survival
Descriptive Note : Scientific rept.
Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Personal Author(s) : Zeman, G H ; Jones, S R ; George, R E ; Levin, S G
Report Date : Feb 1973
Pagination or Media Count : 16
Abstract : Mice were unilaterally irradiated in either a fission neutron or gamma ray field at various dose rates. Jejunal crypt stem cell survival was analyzed by the multitarget single-hit survival model, which yielded excellent fitting survival curves. At the 1 percent survival level, gamma rays were found to be 20 percent more effective in destroying cells when delivered in a brief pulse of radiation than when delivered at lower dose rates (40 rads/minute or 250 rads/minute). Increased cell survival was not observed for low dose rate neutrons. Do values obtained were consistent with the findings of similar studies; however, survival curve intercepts were found to be lower than previous estimates.
Descriptors : *GASTROINTESTINAL SYSTEM , *NEUTRON CAPTURE GAMMA RAYS , *RADIATION INJURIES , CELLS(BIOLOGY) , DOSE RATE , RADIATION DOSAGE , SURVIVAL(PERSONNEL)
Subject Categories : Radiobiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE