Accession Number : AD0764971


Title :   The Relative Effectiveness of Fission Neutrons for Gastrointestinal Damage in Mice: Jejunal Crypt Stem Cell Survival


Descriptive Note : Scientific rept.


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Zeman, G H ; Jones, S R ; George, R E ; Levin, S G


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD0764971


Report Date : Feb 1973


Pagination or Media Count : 16


Abstract : Mice were unilaterally irradiated in either a fission neutron or gamma ray field at various dose rates. Jejunal crypt stem cell survival was analyzed by the multitarget single-hit survival model, which yielded excellent fitting survival curves. At the 1 percent survival level, gamma rays were found to be 20 percent more effective in destroying cells when delivered in a brief pulse of radiation than when delivered at lower dose rates (40 rads/minute or 250 rads/minute). Increased cell survival was not observed for low dose rate neutrons. Do values obtained were consistent with the findings of similar studies; however, survival curve intercepts were found to be lower than previous estimates.


Descriptors :   *GASTROINTESTINAL SYSTEM, *NEUTRON CAPTURE GAMMA RAYS, *RADIATION INJURIES, CELLS(BIOLOGY), DOSE RATE, RADIATION DOSAGE, SURVIVAL(PERSONNEL)


Subject Categories : Radiobiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE