Accession Number : AD0757324


Title :   Neurochemical Changes in Specific Regions of Rat Brain During Different Phases of Conditioning,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Catravas,G. N. ; McFarland,W. L. ; Teitelbaum,H.


Report Date : OCT 1972


Pagination or Media Count : 15


Abstract : The activity changes of RNA polymerase, choline acetyl transferase, acetylcholinesterase and monoamine oxidase in five brain areas were investigated in groups of water deprived rats trained to run for water reward, extinguished after training or retrained after extinction. Marked increases in RNA polymerase and choline acetyl transferase activities were observed in the hippocampus of the experimental animals. A pronounced increase in the activity of RNA polymerase was also found in the posterior hypothalamus of trained rats. No significant changes in the activities of the other enzymes tested were observed as a result of training. (Author)


Descriptors :   (*CONDITIONED RESPONSE, BIOCHEMISTRY), (*BRAIN, BIOCHEMISTRY), ENZYMES, TRAINING, BEHAVIOR, CENTRAL NERVOUS SYSTEM, NEUROLOGY


Subject Categories : PSYCHOLOGY
      BIOCHEMISRTY


Distribution Statement : APPROVED FOR PUBLIC RELEASE