Accession Number : AD0746168


Title :   Effects of Pulsed Gamma-Neutron Irradiation on the EEG and Behavior of the Monkey,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : McFarland,W. L. ; Levin,S. G.


Report Date : APR 1972


Pagination or Media Count : 44


Abstract : Cortical EEG recording leads were implanted in seven rhesus monkeys (Macaca mulatta). The monkeys were then trained to perform a visual discrimination task. After the animals had been trained to acceptable levels of performance, blood pressure measuring devices were surgically implanted. Two weeks after surgery the monkeys were irradiated with a single 2500-rad whole-body pulse of mixed gamma-neutron radiation from the AFRRI-TRIGA reactor. EEG, behavioral, and cardiovascular parameters were continuously monitored and recorded on magnetic tape. Relationships between these EEG measures, behavioral changes, and cardiovascular alternations were then studied both preirradiation and postirradiation. Some degree of apparent relationship was found between changes in the EEG measures after irradiation and changes in performance, particularly during the early transient incapacitation (ETI) period. This relationship could not be well established in the period following ETI or between behavioral and cardiovascular changes. (Author)


Descriptors :   (*RADIATION EFFECTS, *CENTRAL NERVOUS SYSTEM), CARDIOVASCULAR SYSTEM, GAMMA RAYS, NEUTRONS, WHOLE BODY IRRADIATION, BEHAVIOR, ELECTROENCEPHALOGRAPHY, EXPERIMENTAL DATA, MONKEYS


Subject Categories : RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE