Accession Number : AD0742075
Title : Performance of Trained Beagles after Supralethal Doses of Radiation
Descriptive Note : Scientific rept.
Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Personal Author(s) : Chaput, R L ; Kovacic, R T ; Barron, E L
Report Date : Feb 1972
Pagination or Media Count : 24
Abstract : Nine beagle dogs were trained by shock avoidance conditioning to work a discrimination problem cued by visual and auditory stimuli. The animals received 5200- to 17,600-rad midline tissue doses of pulsed mixed gamma-neutron radiation, and their postirradiation performance was evaluated. During the first 60 minutes after irradiation, random, brief periods of performance decrement frequently occurred. Dogs that received less than 10,000 rads performed at or near preirradiation levels several days until they became permanently incapacitated shortly before death. After doses of 10,000 rads or more most dogs performed satisfactorily for only a few minutes to hours. Their condition then worsened precipitously and the dogs died shortly thereafter.
Descriptors : *RADIATION DOSAGE , *RADIATION TOLERANCE , DOGS , EXPERIMENTAL DATA , MORTALITY RATE , PERFORMANCE(HUMAN) , PERMISSIBLE DOSAGE , RADIATION EFFECTS
Subject Categories : Radiobiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE