Accession Number : AD0729259


Title :   Behavior and Physiology of the Monkey 'Macaca Mulatta' Following 2500 Rads of Pulsed Mixed Gamma-Neutron Radiation


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Turbyfill, C L ; Roudon, R M ; Kieffer, V A


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD0729259


Report Date : Aug 1971


Pagination or Media Count : 29


Abstract : Six monkeys, which had been trained to perform a shock motivated visual discrimination task, and which had been surgically implanted to monitor aortic and venous pressures, carotid flow, heart rate and respiratory rate were irradiated with a 2500-rad midline tissue doses of mixed gamma-neutron radiation. Four of the six animals displayed an early performance decrement (less than 90 percent correct responses) within a few minutes following irradiation. One animal showed no performance decrement, and one animal made only five responses and then ceased to perform at all following irradiation. Animals which displayed a performance decrement suffered an acute decrease in aortic pressure. The first physiological indication of the ensuing incapacitation period was a rapid fall of diastolic pressure followed by a decrease in systolic pressure. A second period of behavioral decrement was observed in five of the six animals at approximately 40-45 minutes postirradiation. The respiratory rate was, in general, significantly increased following irradiation. No significant changes were observed in carotid flow or venous pressure.


Descriptors :   *BEHAVIOR, *PHYSIOLOGY, *WHOLE BODY IRRADIATION, BLOOD PRESSURE, GAMMA RAYS, MONKEYS, NEUTRONS, PULSE RATE, RADIATION EFFECTS, RESPIRATION


Subject Categories : Radiobiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE