Accession Number : AD0717591


Title :   Beagle and Miniature Pig Response to Partial Body Irradiation: Dose Relationships.


Descriptive Note : Technical note,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Thorp,J. W.


Report Date : OCT 1970


Pagination or Media Count : 13


Abstract : Beagles and miniature pigs were exposed individually to a pulse of mixed gamma-neutron radiation. Either the head or trunk was shielded, and the midline tissue dose behind the shield (at the middle of the head or trunk) was less than 7 percent of the dose to the same point when no shield was in place. After exposure, the presence or absence of clinical signs of central nervous system damage and the ability to maintain an upright position in a slowly rotating box were used to evaluate the dogs' response. Miniature pigs were evaluated by measuring their performance of a learned, shock avoidance task in a two-chambered shuttlebox. Early incapacitation did not occur in head-shielded dogs or pigs that received up to 25,000 rads or 13,000 rads, respectively, to the middle of the trunk. (Author)


Descriptors :   (*PARTIAL BODY IRRADIATION, RESPONSE(BIOLOGY)), (*RADIATION EFFECTS, RADIATION DOSAGE), DOGS, SWINE, CENTRAL NERVOUS SYSTEM, PERFORMANCE(HUMAN)


Subject Categories : RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE