Accession Number : AD0709920


Title :   CARDIOVASCULAR RESPONSE OF BEAGLES TO A SUPRALETHAL DOSE OF MIXED GAMMA-NEUTRON RADIATION,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Turbyfill,C. L. ; Thorp,J. W. ; Wise,D.


Report Date : MAY 1970


Pagination or Media Count : 14


Abstract : Unshielded, head-shielded or trunk-shielded beagles were irradiated with a 19,000-rad midline tissue dose of pulsed mixed gamma-neutron radiation. The cardiovascular response of the beagle and its alteration by shielding were evaluated. Arterial pressure, blood volume, heart rate, and some plasma chemistry values were determined before and for 1 hour following irradiation. Immediately after irradiation the blood pressure increased in all groups. This prompt hypertension gradually decreased until by 4 minutes postirradiation near normal values were reached; however, the arterial pressure of the head-shielded group declined further and remained lower than those of the unshielded and trunk-shielded animals. In general, this difference was statistically significant beyond 8 minutes postirradiation. No significant difference among the three groups was found in the blood volume, heart rate, hematocrit, or serum chemistry values studied. (Author)


Descriptors :   (*RADIATION EFFECTS, *CARDIOVASCULAR SYSTEM), PHYSIOLOGY, GAMMA RAYS, NUCLEAR RADIATION, BLOOD PRESSURE, BLOOD VOLUME, HEART, HEMATOLOGY, BLOOD CHEMISTRY, SUBLETHAL DOSAGE, PARTIAL BODY IRRADIATION, WHOLE BODY IRRADIATION, HYPERTENSION, DOGS


Subject Categories : RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE