Accession Number : AD0695771


Title :   MINIATURE PIG INCAPACITATION AND PERFORMANCE DECREMENT AFTER MIXED GAMMA-NEUTRON IRRADIATION,


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Chaput,R. L. ; Wise,D.


Report Date : SEP 1969


Pagination or Media Count : 25


Abstract : Miniature pigs were trained by shock avoidance conditioning to traverse, on cue, a two-chambered shuttlebox and performance was evaluated after the pigs received mid-line tissue doses of pulsed, mixed gamma-neutron radiations ranging from 1000 to 14,700 rads. At 2400 rads or more, most pigs were incapacitated with severe convulsions almost immediately after irradiation. At doses of 2400 to 5000 rads this incapacitation often lasted less than 5 minutes after which the animals began to recover and perform. At higher doses, most animals were more severely affected. They became comatose and did not begin to recover until 15 to 50 minutes postirradiation. After recovering from early transient incapacitation the pigs worked for a time at relatively normal levels. Later their performance degenerated and the pigs became permanently incapacitated a few hours before death. At doses of 7600 rads and higher, some of the animals recovered only partially from the early transient incapacitation before becoming permanently incapacitated; and at 13,200 rads or more, most animals were permanently incapacitated immediately after irradiation. (Author)


Descriptors :   (*RADIATION EFFECTS, *SWINE), RESPONSE, RADIATION DOSAGE, RADIATION TOLERANCE, PATHOLOGY, EXPOSURE(PHYSIOLOGY), STATISTICAL ANALYSIS, GAMMA RAYS, STIMULATION(PHYSIOLOGY), NEUTRONS


Subject Categories : RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE