Accession Number : AD0678366
Title : ACUTE MORTALITY OF CHINCHILLAS EXPOSED TO MIXED GAMMA-NEUTRON RADIATIONS OR 250 KVP X RAYS
Descriptive Note : Scientific rept.
Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD
Personal Author(s) : Strike, T A ; Seigneur, L J
Report Date : Apr 1968
Pagination or Media Count : 24
Abstract : The chinchilla's acute mortality response to mixed gamma-neutron radiations of the AFRRI-TRIGA reactor and to 250 kVp x rays was studied. Unilateral whole body irradiations were accomplished at doses from 200 to 639 rads of mixed gamma-neutron radiations and from 357 to 1786 rads of x rays. All radiations were delivered at approximately 20 rads/min, and doses are reported as midline tissue doses. The LD50/30 values calculated for the mixed gamma- neutron radiations and for the x rays were 295 and 490 rads, respectively. Using 30-day median lethality as the end point, the RBE of the mixed gamma- neutron radiations was 1.7. The wide lethal dose range obtained was attributed to a high degree of variation in age of the chinchillas. In contrast to previous experience in rodents, the chinchilla showed a relative resistance to the classically described gastrointestinal modality of radiation death.
Descriptors : *RADIATION EFFECTS , *RODENTS , SURVIVAL(PERSONNEL) , WHOLE BODY IRRADIATION , LETHAL DOSAGE , NEUTRONS , FAST NEUTRONS , GAMMA RAYS , X RAYS , DOSE RATE
Subject Categories : Biology
Distribution Statement : APPROVED FOR PUBLIC RELEASE