Accession Number : AD0678366


Title :   ACUTE MORTALITY OF CHINCHILLAS EXPOSED TO MIXED GAMMA-NEUTRON RADIATIONS OR 250 KVP X RAYS


Descriptive Note : Scientific rept.


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Strike, T. A. ; Seigneur, L. J.


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD0678366


Report Date : APR 1968


Pagination or Media Count : 24


Abstract : The chinchilla's acute mortality response to mixed gamma-neutron radiations of the AFRRI-TRIGA reactor and to 250 kVp x rays was studied. Unilateral whole body irradiations were accomplished at doses from 200 to 639 rads of mixed gamma-neutron radiations and from 357 to 1786 rads of x rays. All radiations were delivered at approximately 20 rads/min, and doses are reported as midline tissue doses. The LD50/30 values calculated for the mixed gamma- neutron radiations and for the x rays were 295 and 490 rads, respectively. Using 30-day median lethality as the end point, the RBE of the mixed gamma- neutron radiations was 1.7. The wide lethal dose range obtained was attributed to a high degree of variation in age of the chinchillas. In contrast to previous experience in rodents, the chinchilla showed a relative resistance to the classically described gastrointestinal modality of radiation death.


Descriptors :   *RADIATION EFFECTS, *RODENTS, SURVIVAL(PERSONNEL), WHOLE BODY IRRADIATION, LETHAL DOSAGE, NEUTRONS, FAST NEUTRONS, GAMMA RAYS, X RAYS, DOSE RATE


Subject Categories : BIOLOGY
      RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE