Accession Number : AD0678365


Title :   ACUTE MORTALITY OF MICE AND RATS EXPOSED TO MIXED GAMMA-NEUTRON RADIATIONS OR TO X RAYS


Descriptive Note : Scientific rept.


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Strike, T. A. ; Seigneur, L. J. ; Stanley, R. E.


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD0678365


Report Date : APR 1968


Pagination or Media Count : 28


Abstract : Mortality data for C57BL mice and Sprague-Dawley rats were collected as a part of the program to biologically characterize AFRRI-TRIGA reactor radiations and to provide reference information for future studies. Unilateral whole body exposures to mixed gamma-neutron radiations from the reactor or to 250 kVp x rays were carried out over a range of midline tissue doses from 370 to 875 rads. The 30-day median lethal doses were calculated to be 589 and 432 rads for mice exposed to the x rays and to the reactor radiations, respectively. The corresponding values for the rat exposures were 740 and 434 rads. Using the LD50/30 values as the end points for comparison, the reactor radiations were 1.4 and 1.7 times more effective in mice and rats, respectively, than were the x rays. The survival times of the mice and rats exposed to reactor radiations were significantly less than those of the animals exposed to similar doses of x rays.


Descriptors :   *RADIATION EFFECTS, *RODENTS, GAMMA RAYS, MICE, WHOLE BODY IRRADIATION, DOSE RATE, LETHAL DOSAGE, NEUTRONS, FAST NEUTRONS, X RAYS, RATS, SURVIVAL(PERSONNEL)


Subject Categories : BIOLOGY
      RADIOBIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE