Accession Number : AD0658021


Title :   HEMATOLOGY OF THE MONKEY (MACACA MULATTA)


Descriptive Note : Scientific rept.


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Stanley, R. E. ; Cramer, M. B.


Full Text : http://www.dtic.mil/get-tr-doc/pdf?AD=AD0658021


Report Date : DEC 1966


Pagination or Media Count : 19


Abstract : Base line hematological values were determined for 79 male and 62 female monkeys (Macaca mulatta). One group of 5 males and 6 females over 3 years of age was sampled weekly for 40 weeks. A second group of 130 monkeys was subdivided according to sex and age: males vs females, under 3 years of age vs over 3 years of age. These animals were sampled biweekly for 12 weeks. Age- and sex-related influences on the various parameters were evaluated. In the first group, the males' red cell count, hemoglobin, and hematocrit were significantly higher (p < .001) than the corresponding values for females. In females the white cell count, platelet count and erythrocyte sedimentation rate were significantly higher (.05 > P > .01) than in males. In the second group, sex-related differences were seen in both age categories. Males under 3 years had significantly higher (p < .01) hemoglobin, hematocrit, lymphocyte and clotting time values than females of the same age group. In females under 3 years, the segmented neutrophil value was higher (p < .01) than in males under 3 years. In the animals over 3 years of age, males had higher values for red cell count, hemoglobin, hematocrit, lymphocyte, clotting time (all p < .01) and white cell count (.05 > p > .01). As in the younger age group, the segmented neutrophil value was higher (p < .01) in females. Three age-related differences were found. Males over 3 years had a higher red cell count (.05 > p > .01) but a lower hemoglobin (p < .01) than males under 3 years. Females under 3 years had a higher white cell count (p < .01) than the older females.


Descriptors :   *MONKEYS, *HEMATOLOGY, HEMOGLOBIN, ERYTHROCYTES, LYMPHOCYTES, FEMALES, SEX, LEUKOCYTES, BLOOD COUNTS, BLOOD PLATELETS, BLOOD ANALYSIS, BLOOD COAGULATION, HEMATOCRIT, AGING(PHYSIOLOGY), MALES


Subject Categories : ANATOMY AND PHYSIOLOGY


Distribution Statement : APPROVED FOR PUBLIC RELEASE