Accession Number : AD0658021


Title :   HEMATOLOGY OF THE MONKEY (MACACA MULATTA)


Descriptive Note : Scientific rept.


Corporate Author : ARMED FORCES RADIOBIOLOGY RESEARCH INST BETHESDA MD


Personal Author(s) : Stanley, R E ; Cramer, M B


Full Text : http://www.dtic.mil/dtic/tr/fulltext/u2/658021.pdf


Report Date : Dec 1966


Pagination or Media Count : 19


Abstract : Base line hematological values were determined for 79 male and 62 female monkeys (Macaca mulatta). One group of 5 males and 6 females over 3 years of age was sampled weekly for 40 weeks. A second group of 130 monkeys was subdivided according to sex and age: males vs females, under 3 years of age vs over 3 years of age. These animals were sampled biweekly for 12 weeks. Age- and sex-related influences on the various parameters were evaluated. In the first group, the males' red cell count, hemoglobin, and hematocrit were significantly higher (p .001) than the corresponding values for females. In females the white cell count, platelet count and erythrocyte sedimentation rate were significantly higher (.05 P .01) than in males. In the second group, sex-related differences were seen in both age categories. Males under 3 years had significantly higher (p .01) hemoglobin, hematocrit, lymphocyte and clotting time values than females of the same age group. In females under 3 years, the segmented neutrophil value was higher (p .01) than in males under 3 years. In the animals over 3 years of age, males had higher values for red cell count, hemoglobin, hematocrit, lymphocyte, clotting time (all p .01) and white cell count (.05 p .01). As in the younger age group, the segmented neutrophil value was higher (p .01) in females. Three age-related differences were found. Males over 3 years had a higher red cell count (.05 p .01) but a lower hemoglobin (p .01) than males under 3 years. Females under 3 years had a higher white cell count (p .01) than the older females.


Descriptors :   *MONKEYS , *HEMATOLOGY , HEMOGLOBIN , ERYTHROCYTES , LYMPHOCYTES , FEMALES , SEX , LEUKOCYTES , BLOOD COUNTS , BLOOD PLATELETS , BLOOD ANALYSIS , BLOOD COAGULATION , HEMATOCRIT , AGING(PHYSIOLOGY) , MALES


Subject Categories : Anatomy and Physiology


Distribution Statement : APPROVED FOR PUBLIC RELEASE